Diffraction
MX
Macromolecular crystallography (MX) provides high-resolution structural models of large biological molecules.
Proteins, DNA, RNA, and other large biomolecules in crystalline form can be investigated using x-ray diffraction techniques.
MX is the most common industry use of synchrotrons worldwide and is used by the pharmaceutical industry for drug design and pre-clinical development.
The Swiss Light Source at the Paul Scherrer Institute hosts 3 instruments that are amongst the most powerful and productive macromolecular crystallography beamlines in the world, and have contributed to Nobel prize winning science. The instruments are highly automated and support high throughput screening.
A Macromolecular Crystallisation Facility is situated at the PXIII beamline to produce and optimise macromolecular microcrystals and nanocrystals for x-ray diffraction experiments at the forefront of structural biology.
APPLICATION SECTORS
Healthy ageing